Massive study tracks 3,294 ACL patients to uncover keys to better recovery

NCT ID NCT00463099

Ongoing Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jan 28, 2026 · Last updated Apr 30, 2026 · Updated 14 times

Summary

This study follows over 3,200 people who had surgery for a torn ACL. Researchers want to see how things like activity level and other risk factors affect knee function, arthritis, and the chance of re-injury. Participants complete surveys and have X-rays over time to track their progress.

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Contacts and locations

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Locations

Cleveland Clinic

Cleveland, Ohio, 44195, United States
Duke University

Durham, North Carolina, 27710, United States
Hospital for Special Surgery

New York, New York, 10021, United States
The Ohio State University

Columbus, Ohio, 43221, United States
University of Colorado

Boulder, Colorado, 80304, United States
University of Iowa

Iowa City, Iowa, 52242, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Washington University at St. Louis

St Louis, Missouri, 63141, United States

Conditions

Explore the condition pages connected to this study.

RUPTURE OF ANTERIOR CRUCIATE LIGAMENT RUPTURE OF ANTERIOR CRUCIATE LIGAMENT