Massive study tracks 3,000+ ACL patients to predict knee outcomes

NCT ID NCT00463099

Ongoing Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jan 28, 2026 · Last updated Jun 17, 2026 · Updated 23 times

Summary

This study follows over 3,200 people who had surgery for a torn ACL. Researchers want to learn which factors affect knee function, arthritis, and the chance of re-injury. Participants complete surveys and have X-rays over time to track their recovery.

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Contacts and locations

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Locations

Cleveland Clinic

Cleveland, Ohio, 44195, United States
Duke University

Durham, North Carolina, 27710, United States
Hospital for Special Surgery

New York, New York, 10021, United States
The Ohio State University

Columbus, Ohio, 43221, United States
University of Colorado

Boulder, Colorado, 80304, United States
University of Iowa

Iowa City, Iowa, 52242, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Washington University at St. Louis

St Louis, Missouri, 63141, United States

Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries Knee Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RUPTURE OF ANTERIOR CRUCIATE LIGAMENT RUPTURE OF ANTERIOR CRUCIATE LIGAMENT