Walking study aims to unlock secrets of stiff muscles after stroke
NCT ID NCT07467382
First seen Jun 25, 2026 · Last updated Sep 16, 2026 · Updated 3 times
Summary
This study looks at how the Achilles tendon behaves during walking in people with spastic paresis, a condition causing muscle stiffness after stroke or spinal cord injury. Researchers will measure tendon stiffness, length, and volume using ultrasound and motion analysis. The goal is to better understand walking problems, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help design better rehabilitation therapies for people with walking difficulties after stroke or spinal cord injury.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly improve symptoms, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A maximum of 60 subjects will be included. Twenty will be post-stroke patients with hemiparesis, 20 will be post-incomplete spinal cord injury patients, and 20 will be healthy subjects.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Study population: • Cognitive abilities compatible with the experiment: no language or judgement disorders preventing understanding of the research or expression of consent. An aphasia severity score greater than or equal to 3 on the Boston Diagnostic Aphasia Examination (BDAE) scale will be required for inclusion. Post-stroke population: * Adult male or female * Patient who has had a stroke \> 7 days ago * Patient hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and medical rehabilitation department of Nantes University Hospital * Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at the GM level * Patients classified as 3 to 8 on the New Functional Ambulation Classification * Indication to perform a quantified gait analysis as part of clinical management Post-spinal cord injury population: * Adult men or women * Patients with incomplete spinal cord injury graded ASIA AIS C or D from C2 to L5 * Patients hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and occupational therapy department of Nantes University Hospital * Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at GM level * Patients rated 13-20 on the WISCI-II scale * Indication for a quantified gait analysis as part of clinical care Healthy population: • Adult men or women with no nervous system disorders. Exclusion Criteria: Post-stroke and post-spinal cord injury population: * Minors; * History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g. botulinum toxin) in the plantar flexors \< 6 months; * Patients with a progressive condition that contraindicates exertion (syrinx, cardiovascular instability); * Peripheral pathology of the lower limb in question. Healthy population: * History of calf surgery; * History of muscle injury, fracture or sprain of the lower limb \< 3 months; * History of neurological condition.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Nantes
RECRUITINGNantes, France
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