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New PARP inhibitor trial hopes to shrink Hard-to-Treat cancers

NCT ID NCT06380660

First seen Jan 08, 2026 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This study tests a new drug called ACE-86225106 in people with advanced solid tumors (like ovarian, breast, or prostate cancer) that have BRCA gene mutations. The goal is to see if the drug is safe and can shrink tumors. About 298 adults will take the drug, and researchers will monitor side effects and how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anyang Cancer Hospital

    RECRUITING

    Anyang, Henan, China

  • Chongqing Cancer Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, China

  • First Hospital Affiliated to Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, China

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, China

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, China

  • Hubei Cancer Hospital

    RECRUITING

    Wuhan, Hubei, China

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, China

  • Jinan Central Hospital

    RECRUITING

    Jinan, Shandong, China

  • Qilu Hospital Shangdong University

    RECRUITING

    Jinan, Shandong, China

  • Second Hospital Affiliated to Shanxi Medical University

    RECRUITING

    Taiyuan, Shanxi, China

  • Sun Yat-Sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.