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New drug studied before bladder surgery in Chemo-Unfit patients

NCT ID NCT03837821

First seen Nov 18, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study gives a targeted drug called abemaciclib to 20 people with bladder cancer who cannot have standard chemotherapy. The drug is taken for a short time before surgery to remove the bladder. Researchers compare tumor samples taken before and after treatment to see how the drug affects cancer cell growth and genetic changes. The goal is to learn more about the drug's effects, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UT Southwestern Medical Center - Simmons Comprehensive Cancer Center

    Dallas, Texas, 75390, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.