Could your own blood speed wisdom tooth healing?
NCT ID NCT07761338
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial tests whether a substance made from a patient's own blood, called advanced platelet-rich fibrin (A-PRF), can reduce pain and complications after surgical removal of lower wisdom teeth. Researchers will measure the levels of platelets and growth factors in the A-PRF and compare recovery outcomes in 60 patients. The goal is to see if this natural approach can make the post-surgery experience more comfortable.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- advanced platelet-rich fibrin (A-PRF), a blood-derived concentrate applied to the surgical site
- What this could lead to
- If effective, A-PRF could become a standard way to reduce pain, swelling, and complications after wisdom tooth extractions.
- What could go wrong
- This is a small, early-stage study, and the benefits of A-PRF are not yet proven. Results may not apply to all patients or procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
60 people
The number who actually took part.
- Started
-
Oct 2024
- Finished
-
Jan 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy patients with indication for surgical removal of mandibular third molar
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * indication for surgical removal of mandibular third molar Exclusion Criteria: * breastfeading, pregnancy
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Copenhagen
Copenhagen, Denmark
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Other studies related to the condition(s) this trial covers.
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