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Jaw injection may take the ouch out of wisdom tooth surgery

NCT ID NCT07297264

Symptom relief Sponsor: Shehab Ahmed Hamad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a single injection of betamethasone (a steroid) into the jaw space could reduce pain, swelling, and difficulty opening the mouth after impacted wisdom tooth surgery. Forty healthy adults with similar wisdom teeth on both sides received the steroid on one side and a placebo on the other. The trial was terminated early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
betamethasone
What this could lead to
If it works, this could offer a simple way to reduce pain, swelling, and jaw stiffness after wisdom tooth surgery.
What could go wrong
The trial was terminated early with only 40 participants, so results may not be reliable. It also only applies to healthy people with specific tooth positions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

40 people

The number who actually took part.

Started

Jan 2022

Finished

Mar 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * healthy * no infection * no pain * no limitation of mouth opening * symmetrical bilateral impacted third molars (Mesioangular, CLASS II, Position B Exclusion Criteria: * Infection * systemic disease * smokers * operation time exceeding 30 minutes

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Morbidity Steroid injection Third molars extraction

Contacts and locations

Locations

  • Shehab Ahmed Hamad

    Erbil, 00441, Iraq

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