Glow-in-the-Dark dye could help brain cancer surgery

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age greater than 18 years with no upper age limit * Competent adult patient. * Patient affiliated to the National Health Insurance. * Patient with an intra-cerebral supra-tentorial hemispheric, newly diagnosed and previously untreated, which MRI characteristics are suggestive of a glioblastoma. * Indication for surgical treatment by excision. * Brain tumor location distant from critical functional areas allowing a wide resection of contrast enhancement on imaging, the a priori character completely resectable has been validated by an evaluation committee composed of three surgeons * No-cons contain medical surgery, ASA score below 4. * Patient eligible for further treatment by radiotherapy and concurrent chemotherapy followed by adjuvant chemotherapy according to the so called Stupp scheme (standard protocol of adjuvant chemoradiotherapy) * Negative pregnancy test for women of childbearing age. Exclusion Criteria: * Contraindications to performing an MRI (pacemaker). * Glioblastoma known and previously treated with surgery, radiotherapy and / or chemotherapy. * History of cancer. * Anatomical Location of the tumor-cons indicating a wide excision, neurosurgeon at the discretion of medical officer participating center. * Location tumor in the brain stem, the middle line, the basal ganglia and the posterior cranial fossa. * Patient with cons-indication to the achievement of further treatment with radiotherapy and concurrent chemotherapy followed by adjuvant chemotherapy according to the scheme proposed by Stupp. (1) * Patients with porphyria, renal insufficiency (creatinine\> 177 μmolL), liver insufficency(gamma glutamyl transpeptidase\> 100 U / L, prothrombin time \<60%, bilirubin\> 51μmol / L). * Patient refused to sign an informed consent form. * Ongoing participation of the patient to another clinical trial.