University Of Wisconsin, Madison

This study is testing the safety and initial effects of a late surfactant treatment combined with budesonide for extremely premature infants who are still on a breathing machine at 7-14 days old. The goal is to see if this approach can help prevent a serious, chronic lung conditi…

This study is testing a text- and web-based tool called FamilyCHESS, designed for a person with opioid use disorder and a supportive family member or friend. The goal is to see if using this tool helps the patient start medication treatment (MOUD) sooner and stay on it longer. Re…

This study is testing a new combination of two drugs, ASTX727 (a pill) and retifanlimab (an IV infusion), for people with advanced Merkel cell carcinoma, a rare and aggressive skin cancer. It is specifically for patients whose cancer has continued to grow or spread despite receiv…

This study aims to see if giving an extra dose of caffeine helps improve oxygen levels in the kidneys of very premature babies. It will involve about 102 babies born before 30 weeks. Researchers want to find out if this extra dose can reduce kidney injury without harming the baby…

This early-stage trial is testing a modified stem cell transplant for children and young adults with serious, non-cancerous blood diseases like sickle cell anemia and bone marrow failure syndromes. The goal is to make the transplant safer by using a new method to filter the donor…

This study will test whether adding a special education and coaching program to regular Special Olympics activities helps adults with intellectual and developmental disabilities get better healthcare. Researchers will compare the new program against standard Special Olympics heal…

This study aims to find the most effective way to help Black adults quit smoking long-term. Researchers will compare three different support programs: standard quitline services, a more intensive culturally tailored program, and that same intensive program with financial incentiv…

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' improves mood and wellbeing. Researchers want to know if the benefits come from the psychedelic experience itself or from direct effects on the brain. Up to 120 healthy adults with sub-optimal wel…

This study aims to see if learning about well-being through a meditation app can improve the thoughts, feelings, and relationship satisfaction of romantic couples. Researchers will enroll 2,000 adults in long-term relationships where one partner has symptoms of depression. One pa…

This study aims to see if a free mindfulness and well-being smartphone app is practical, safe, and shows early signs of helping adults who have recently had suicidal thoughts. About 50 participants will use the app for 4 weeks, completing lessons and brief surveys. The goal is to…

This small pilot study is testing whether a mobile phone app can effectively deliver depression treatment. Eight African American adults with depression will attend six weekly 90-minute mental health classes through the app and complete regular surveys. The goal is to see if this…

This study is testing if a simple communication strategy can help children with cerebral palsy speak more clearly. Kids ages 7-17 will learn to point to letters or pictures on a board while they talk, which may give listeners helpful clues. Researchers will measure if this one-ti…

This study is testing whether a new AI tool can reduce the heavy paperwork burden on nurses. The software listens to conversations between nurses and patients and automatically drafts parts of the patient's digital chart. Researchers will measure if this saves nurses time on docu…

This study aims to understand how Metabolic Syndrome (a cluster of conditions like high blood pressure and obesity) affects blood flow to the brain. Researchers believe it may reduce blood flow more in women than in men, partly due to differences in how a specific enzyme works. T…

This study is testing a new type of X-ray machine to see if it can take clearer pictures during image-guided medical procedures. Researchers will compare images from the new machine to standard imaging to see if it helps doctors better see things like calcium deposits or metal. T…

This study is testing a small device that attaches to shoes to monitor walking patterns in healthy adults aged 65 and older. Researchers want to see how accurately the device measures walking speed, stride, and stair climbing compared to a professional lab system. Participants wi…

This study aims to compare two different medical devices used to measure swallowing pressure and function. Researchers will test both systems on 25 healthy adult volunteers during a single visit to see how the measurements differ. The goal is to help standardize how doctors diagn…

This study aims to understand if a new dairy ingredient is as good a source of choline as eggs for post-menopausal women. Researchers will compare how the body absorbs and uses choline from a whey protein supplement versus whole egg powder. Participants will drink chocolate-flavo…

This study aims to understand how often and why common cold viruses (rhinoviruses) cause severe breathing problems that require children to be hospitalized. Researchers will follow healthy children in the community and compare them to children who are hospitalized with severe res…

This study aims to understand how learning your Alzheimer's disease biomarker test results affects your emotional well-being, daily behaviors, and future health decisions. Researchers will follow 240 adults aged 50+ who are at risk for Alzheimer's and have completed brain scans. …

This early-stage study is testing whether a drug called apalutamide, which is used for prostate cancer, affects a specific protein (EGFR) in bladder cancer cells. Researchers want to see if blocking male hormones influences this protein, which is linked to cancer progression. The…

This study aims to see if taking an oral probiotic supplement is safe and practical for people who have early Alzheimer's disease or are at risk for it. Researchers will enroll 40 participants, some with mild memory problems and some without, to take the supplement for up to a ye…

This study is testing new computer software designed to improve MRI brain scans. Researchers want to see if the software can make scans faster, reduce noise, improve image quality, and make the process easier for both patients and technicians. About 131 adults will have one 60-mi…