University Of Vermont
Clinical trials sponsored by University Of Vermont, explained in plain language.
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Doctors try injecting chemo straight into lung tumors
Disease control CompletedThis early safety study tested whether injecting the chemotherapy drug cisplatin directly into lung tumors before surgery is safe and tolerable. Six patients with early-stage, operable non-small cell lung cancer received the injection during a single bronchoscopy procedure. The g…
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Can 'Light' cigarettes help expectant mothers cut back?
Disease control CompletedThis study tested whether switching pregnant women who smoke to cigarettes with very low nicotine helps them smoke fewer cigarettes each day. Thirty pregnant smokers were randomly assigned to either keep smoking their regular brand or switch to special low-nicotine cigarettes for…
Phase: PHASE1, PHASE2 • Sponsor: University of Vermont • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Cash for clean tests: pilot study pays people to stay off drugs
Disease control CompletedThis small pilot study tested whether offering money could help people who use stimulants like meth or cocaine to stop. Researchers worked with 27 people who visited a syringe exchange program. One group could earn cash for providing drug-free urine tests, while another group jus…
Phase: NA • Sponsor: University of Vermont • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Weekly meal deliveries ease hunger and depression for those battling opioid addiction
Symptom relief CompletedThis study tested whether delivering weekly meals could help people with opioid use disorder who struggle to get enough food. Fifty adults receiving treatment for opioid addiction were randomly assigned to receive either basic nutrition information or that information plus 12 wee…
Phase: NA • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Antioxidant pill tested to ease breathing in obese asthma patients
Symptom relief CompletedThis small, early-stage study tested whether a daily antioxidant pill called MitoQ could improve breathing problems in adults with both obesity and poorly controlled asthma. Over 14 weeks, 40 participants took either MitoQ or a placebo pill. The main goal was to see if MitoQ redu…
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Can a phone app prescribe exercise to ease asthma?
Symptom relief CompletedThis small pilot study tested whether a 12-week, doctor-prescribed exercise program delivered through a smartphone app is practical and acceptable for adults who have both obesity and poorly controlled asthma. Twenty participants used the app to follow a personalized exercise pla…
Phase: NA • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Menopause brain fog: a clue to future Alzheimer's?
Knowledge-focused CompletedThis study aimed to understand why some women experience memory and thinking changes after menopause and how this might be linked to a higher risk of Alzheimer's disease later in life. Researchers studied 120 healthy postmenopausal women, using brain scans and memory tests to see…
Phase: EARLY_PHASE1 • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists probe hidden cause of slow recovery after knee surgery
Knowledge-focused CompletedThis study aimed to understand why leg muscles get smaller and weaker after knee replacement surgery, which slows down recovery. Researchers measured muscle changes in 23 patients with severe knee arthritis before and after their operation. They also tested whether using a device…
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Brain scan study tests Choline's effect after menopause
Knowledge-focused CompletedThis study investigated whether a single large dose of choline, an essential nutrient, affects brain activity in postmenopausal women. Researchers gave 38 healthy women either choline or a placebo and then used brain scans to measure activity during memory tasks. The goal was to …
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:20 UTC