University Of South Florida

This trial tests three deep brain stimulation (DBS) settings in people with Parkinson's disease who already have a Boston Scientific Vercise system implanted. The settings are pure anodic, pure cathodic, and a mix of both. Researchers want to see which setting offers the best sym…

This study tests a program that teaches parents how to help their child, a childhood cancer survivor, eat healthy and exercise more. The goal is to prevent or reduce obesity, which is a major risk for heart disease in these children. About 520 families will take part in one of tw…

This study tests whether a daily postbiotic gummy can help restore healthy gut bacteria after surgery for colon or other gastrointestinal cancers. Thirty adults scheduled for surgery will be randomly assigned to receive either the postbiotic or a placebo gummy for two weeks after…

This study tests a program that connects pregnant women with opioid use disorder to a team of doctors, peer supporters, and community resources like doulas and home visiting. The goal is to improve treatment during pregnancy and reduce the need for medication in newborns experien…

This trial tests whether a specific type of computerized cognitive training, called speed-of-processing training, can delay the onset of mild cognitive impairment or dementia in adults aged 65 and older. Participants will complete 45 sessions of either the training or a general c…

This study looks at whether a non-surgical treatment called spinal decompression can help people with chronic low back pain. About 42 adults with back pain from disc problems or sciatica will receive the treatment over 12 weeks. Researchers will use MRI scans and movement tests t…

This study looks at whether taking phenazopyridine (AZO) can reduce pain after urodynamic testing, a procedure that checks how well the bladder works. About 66 adults will take the drug or a placebo and rate their pain and anxiety levels. The goal is to find a simple way to make …

This study tests an online self-help program called Together After Cancer for Latina breast cancer survivors and their intimate partners. The program includes brief coach calls and aims to improve the survivor's quality of life and the couple's relationship satisfaction. About 48…

This study looks at whether using a mindfulness app on a smartphone for 8 weeks can improve mental health in Korean immigrants aged 60 and older. Participants use the app for about 10-15 minutes daily and have weekly check-ins. The goal is to see if the app is easy to use and hel…

This study tests whether 8 weeks of acceptance and commitment therapy (ACT) delivered via Zoom can help reduce depression in people with spinal cord injuries. 140 participants with mild or worse depressive symptoms will be randomly assigned to either ACT or a wait-list that conti…

This study follows 250 adults with alcohol use disorder who receive 12 weeks of talk therapy. Researchers will track their drinking habits, negative consequences, and quality of life for a year after treatment. The goal is to better understand the different ways people recover an…