University Of Oklahoma

This study tests the safety and effectiveness of combining a short course of radiation (QUAD SHOT) with the immunotherapy drug pembrolizumab in 30 adults with recurrent head and neck cancer. The goal is to control the cancer and improve quality of life. Participants receive both …

This early-phase study tests the safety of combining two drugs, avelumab and AVB-S6-500, in adults with advanced urothelial carcinoma (bladder cancer) that has spread or cannot be removed by surgery. Participants must have already tried at least one platinum-based chemotherapy. T…

This study tests whether a smartphone app designed for people with serious mental illness can help them quit smoking. About 64 adults who smoke heavily and have a mental illness will use one of two special apps or a standard app for 5 weeks. All participants also get nicotine pat…

This study works with the Choctaw Nation to help more people get screened for lung cancer. Lung cancer is a leading cause of death in American Indian and Alaska Native communities, and screening can catch it early. The program will identify who is eligible, help them schedule and…

This study planned to test whether an electromagnetic resonator could change how the autonomic nervous system works in people with heart failure. It would have included 20 heart failure patients and 20 healthy volunteers. However, the study was withdrawn before enrolling any part…