University Of Massachusetts, Worcester
Clinical trials sponsored by University Of Massachusetts, Worcester, explained in plain language.
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Phone apps aim to boost HIV care and cut drinking in zambian youth
Disease control OngoingThis study is testing two mobile health programs for young adults (ages 18-24) in Zambia who are living with HIV and also have risky alcohol use. The goal is to see if these phone-based tools are acceptable and practical for improving HIV medication adherence and reducing substan…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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New program aims to get cancer survivors moving to fight heart disease
Disease control ENROLLING_BY_INVITATIONThis study tests a clinic-based program called ActivityChoice that helps cancer survivors become more physically active to lower their risk of heart disease. About 114 adult cancer survivors will be offered a choice of group in-person, group virtual, or self-monitored digital exe…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 26, 2026 03:03 UTC
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Can storytelling lower blood pressure? vietnam study aims to find out
Disease control ENROLLING_BY_INVITATIONThis study tests a community program to help 700 adults in a large Vietnamese city better control their high blood pressure. Participants will receive support from community health workers and watch storytelling videos about managing hypertension. The goal is to see if these tool…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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New tool aims to boost stroke prevention in heart patients
Disease control ENROLLING_BY_INVITATIONThis study tests a computer alert that reminds doctors to prescribe blood thinners for patients with atrial fibrillation, a heart condition that raises stroke risk. About 5,000 patients and their doctors are taking part. The goal is to see if the alert helps more patients start a…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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ER app aims to curb suicide risk in thousands
Disease control ENROLLING_BY_INVITATIONThis study tests a digital platform called Jaspr Health in emergency rooms for adults who are at risk of suicide. The platform provides evidence-based support during waiting time, aiming to reduce suicide attempts and related hospital visits. About 28,000 participants will be fol…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 20, 2026 12:03 UTC
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Could a traditional puerto rican diet tame Crohn's Flare-Ups?
Disease control OngoingThis study tests whether a special anti-inflammatory diet, adapted for Puerto Rican foods and preferences, can help people with Crohn's disease feel better and reduce inflammation. About 150 adults with mild to moderate Crohn's will follow either the DAIN diet or their usual diet…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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Support team boosts diabetes control with High-Tech monitors
Disease control ENROLLING_BY_INVITATIONThis study tests whether a team of clinical pharmacists and community health workers can help people with type 2 diabetes improve their blood sugar control using continuous glucose monitors (CGM). About 318 adults aged 25-75 with high blood sugar will be enrolled. The goal is to …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Can better support prevent overdose? new study tests two approaches
Disease control OngoingThis study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION versus working with a Peer Specialist. Researchers will track which approach leads to better treatment engagement, less substance use, and imp…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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Phone apps could boost HIV prevention in vulnerable youth
Prevention OngoingThis study tests whether smartphone-based tools can help young transgender women in Thailand start and stick with HIV pre-exposure prophylaxis (PrEP). About 145 participants aged 16-29 will use mobile interventions and be followed for 6 months. The goal is to see if these digital…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated May 11, 2026 20:38 UTC
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New therapy group aims to help women veterans cut back on drinking
Symptom relief OngoingThis study tests a special therapy group designed for women veterans who struggle with alcohol use. The therapy, called cognitive behavioral therapy (CBT), helps women understand and change their drinking habits. About 162 women will take part, and researchers will check if this …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 26, 2026 03:14 UTC
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New hope for knee replacement pain? radio waves tested in small study
Symptom relief OngoingThis study tests a procedure called radiofrequency ablation to see if it safely reduces chronic knee pain in people who still have pain at least one year after knee replacement surgery. Fourteen adults with ongoing knee pain will receive either the real procedure or a sham (fake)…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 26, 2026 03:05 UTC
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Nose spray vs. syrup: which stops Post-Surgery delirium in children?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a nose spray (dexmedetomidine) or a syrup (midazolam) given before surgery can prevent delirium—confusion and agitation—in children waking up from anesthesia. About 60 children aged 3 months to 9 years having ear tube surgery will take part. The goal is t…
Phase: PHASE4 • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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New study aims to speed up recovery after pacemaker implant
Symptom relief ENROLLING_BY_INVITATIONThis study compares two methods to close the large vein used for a leadless pacemaker implant: a special stitch device versus manual pressure with a figure-of-eight stitch. The goal is to see which stops bleeding faster and helps patients leave the hospital sooner. About 50 adult…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 18, 2026 12:12 UTC
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Avatar app aims to curb binge drinking and suicidal thoughts in young adults
Symptom relief OngoingThis study tests a new smartphone app that uses a friendly avatar guide to help young adults (ages 18-29) who struggle with binge drinking and suicidal thoughts. Ten participants from the emergency department will use the app for 28 days. The goal is to see if the app is easy to …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 18, 2026 12:02 UTC
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Brain games may beat chemo brain fog
Symptom relief OngoingThis study tests if a computer-based brain training program can help breast cancer survivors who have memory and thinking problems after chemotherapy (chemo brain). About 50 survivors will either do the brain training or receive education for 6 weeks. The goal is to see if the tr…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Stories over statistics: new trial uses narratives to close anticoagulation gap in black patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether watching storytelling videos can help African American patients with atrial fibrillation (an irregular heartbeat) start and continue taking blood thinners, which lower stroke risk. About 80 participants will be randomly assigned to view the videos or rece…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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App or nap? study tests digital sleep aid for infants and moms
Knowledge-focused OngoingThis study looks at how using the Huckleberry app, a sleep guidance tool, affects infant sleep and the mental health of mothers. About 120 mothers with babies under 1 year old will answer surveys about sleep, mood, and bonding. The goal is to understand if the app helps, not to t…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Skin-to-Skin care study aims to boost survival of tiny babies in rural india
Knowledge-focused OngoingThis study looks at ways to help mothers of preterm or low birth weight babies keep doing Kangaroo Care (skin-to-skin contact) at home after leaving the hospital in rural India. About 190 mothers and healthcare workers will take part. The goal is to understand what helps or hinde…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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30,000 patients join national registry to improve joint replacement outcomes
Knowledge-focused OngoingThis study is building a large national registry of 30,000 people who are scheduled for hip or knee replacement surgery. The goal is to collect information on pain, physical function, and any complications before and after surgery. By analyzing this data, researchers hope to find…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Can a Body-Positive approach ease weight stigma in pregnancy?
Knowledge-focused OngoingThis study is adapting a program called Health at Every Size (HAES) for use in pregnancy care. The goal is to help pregnant people with a higher body weight feel less judged about their weight and improve their mental health. Ten first-time pregnant women with a BMI over 30 will …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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New program aims to boost lung cancer screening through shared decisions
Knowledge-focused ENROLLING_BY_INVITATIONThis pilot study tests a program called FIX-SDM that helps patients and their primary care doctors talk about and decide on lung cancer screening. About 120 patients and their doctors will take part. The goal is to see if the program increases the number of people who get screene…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC