University Hospitals, Leicester

This study is testing if a special blood filter called the HA380 can help critically ill patients who need life support machines like dialysis or ECMO. The filter aims to remove harmful inflammation-causing substances from the blood, which researchers hope will help patients reco…

This study is testing if a newer way to pace the heart (His bundle pacing) is better and safer than the standard method (right ventricular pacing) for people with a fast, irregular heartbeat (atrial fibrillation) who also have signs of heart failure. About 100 participants will b…

This study is testing a simple, non-invasive bedside device that measures body water content in pregnant women. Researchers want to see if this test can provide useful information about hydration and identify women at risk for pregnancy complications like pre-eclampsia. The study…

This study aims to understand how the COVID-19 pandemic changed the timing and severity of RSV (a virus causing bronchiolitis) in young UK children. It will track up to 3000 children under 2 years old who come to emergency departments with bronchiolitis symptoms. The research wil…

This study aims to discover the genetic causes of bicuspid aortic valve (BAV), a common heart defect where the aortic valve has two leaflets instead of three. Researchers will recruit 700 participants, including people with BAV and their family members, to compare their DNA and i…