Unicancer

This study is testing whether a special imaging scan called SPECT-CT can help doctors decide whether throat cancer patients need radiation treatment on one side or both sides of their neck. Currently, most patients receive radiation to both sides, which causes more side effects a…

This trial aims to improve cancer treatment by matching patients with advanced solid tumors to specific immunotherapies based on a detailed analysis of their individual tumor and immune system. Researchers will use a rapid testing platform called PORTRAIT on fresh blood and tumor…

This study is testing whether adding a new drug called prifetrastat to the standard hormone therapy fulvestrant can help control advanced breast cancer that has stopped responding to other treatments. It is for adults with a specific type of breast cancer (HR+/HER2-) that has spr…

This large international trial is testing if a simple blood test can help doctors personalize chemotherapy after surgery for stage III colon cancer. The test looks for tiny bits of cancer DNA in the blood. If the test is negative, patients may get a shorter, gentler chemo regimen…

This study is for people with colorectal cancer that has spread to the liver and who are at high risk of the cancer returning after surgery. Researchers are testing if delivering a chemotherapy drug (oxaliplatin) directly into the liver's blood supply is more effective at prevent…

This study is testing a new blood test to help doctors choose the best first treatment for advanced lung cancer. It aims to identify patients who can safely receive immunotherapy alone, which can provide long-lasting control, while avoiding the risk of rapid tumor growth that som…

This study is testing if adding a new drug called Mitazalimab to standard chemotherapy (mFOLFOX) works better than chemotherapy alone for people with advanced bile duct cancer that has progressed after initial treatment. About 160 participants will be randomly assigned to receive…

This study is testing if alternating between two newer, targeted cancer drugs can help patients with advanced triple-negative breast cancer live longer than using just one of the drugs. It will involve about 260 adults whose cancer has spread or cannot be removed by surgery. The …

This study is testing whether adding a new drug called ivonescimab to standard chemotherapy works better than the current standard combination for people with advanced colorectal cancer that hasn't spread to the liver. Researchers will compare how long each treatment keeps the ca…

This study aims to see if a genetic test can safely guide treatment decisions for younger women with a common type of early breast cancer. It will compare the standard approach of giving chemotherapy to everyone against a personalized plan where some women receive only hormone th…

This study aims to see if two simple blood tests can find HPV-related throat cancers early, before symptoms appear. It will enroll 10,000 men aged 50 and older with no symptoms. If successful, this could lead to a national screening program to catch these cancers sooner and impro…

This study is testing whether simple, non-invasive 'liquid biopsies' from blood, urine, and stool can safely reduce the need for frequent, uncomfortable colonoscopies in people with Lynch syndrome, a genetic condition that increases cancer risk. It will compare the standard appro…

This study is testing a new type of imaging scan to see if it can predict how well a targeted breast cancer drug works. It involves 30 patients with advanced breast cancer who are already scheduled to receive the drug T-DXd. The goal is to see if this scan can help doctors unders…