Ucb Biopharma Srl

This study is testing whether the drug bimekizumab can help people with palmoplantar pustulosis, a chronic skin condition that causes painful blisters on the palms and soles. About 320 participants will receive either bimekizumab or a placebo for 16 weeks, followed by an open-lab…

This study is testing an investigational drug called galvokimig for adults with moderate-to-severe atopic dermatitis (eczema). Researchers will compare different doses of the drug against a placebo to see which works best at reducing skin inflammation and itching. The trial will …

This study is testing an investigational drug called rozanolixizumab in children aged 2 to 18 who have moderate to severe generalized myasthenia gravis (gMG), a rare autoimmune disease that causes muscle weakness. The main goal is to see if the drug is safe and well-tolerated whe…

This study aims to understand how the medication bimekizumab affects specific genes in the skin of people with moderate to severe plaque psoriasis. It will enroll 90 adults, some with psoriasis alone and some who also have psoriatic arthritis. Researchers will take small skin sam…

This study aims to see if a new injectable drug called bimekizumab works better and is as safe as an existing drug, ustekinumab, for children and teenagers with moderate to severe plaque psoriasis. It will involve about 168 participants aged 6 to 18. The main goal is to see if th…

This study is testing if giving the arthritis drug bimekizumab through an IV (into a vein) works as well as the standard injection under the skin. It will involve about 392 adults with active psoriatic arthritis or axial spondyloarthritis. The main goal is to see if the drug leve…

This study is testing a new, fast-acting inhaled form of alprazolam designed to stop prolonged seizures within 90 seconds and prevent them from coming back for several hours. It's for people aged 12 and older with epilepsy who experience these longer seizure episodes. The goal is…

This study is testing an existing adult arthritis drug called bimekizumab in children and teenagers with specific types of juvenile arthritis. The main goals are to see how much of the drug gets into the bloodstream and to check its safety when given as an injection. The trial wi…

This study aims to understand the long-term safety and side effects of the drug brivaracetam in children and teenagers with absence epilepsy. It will follow 120 participants who have already taken the drug in previous studies to see how well they tolerate it over an extended peri…

This study aims to understand how the drug bimekizumab behaves in the body and how safe it is for teenagers with moderate to severe hidradenitis suppurativa (HS), a painful chronic skin condition. It will enroll about 40 participants aged 12 to 18 who have not responded well to p…

This study aims to learn about the safety, drug levels in the body, and activity of an investigational drug called zilucoplan in children and teenagers (ages 2 to 18) with a rare autoimmune disease called generalized myasthenia gravis (gMG). The study will enroll about 8 particip…

This study is testing an existing drug, rozanolixizumab, in Chinese adults with generalized myasthenia gravis (gMG), a disease that causes severe muscle weakness. The main goal is to see if the drug improves patients' ability to perform daily activities and reduces their muscle w…

This study is testing an investigational drug called dapirolizumab pegol as an add-on to standard lupus medications. It aims to see if the drug can help people with moderate to severe lupus achieve long-term improvement in their disease activity and symptoms like fatigue. The tri…

This is an early-stage study to check if a new drug called UCB5285 is safe for people and how the body handles it. Healthy volunteers will receive either the drug or a placebo (inactive substance) in increasing doses. Researchers will monitor for side effects and measure how long…

This early-stage study aims to check if a new oral medication called UCB0022 is safe for people to take. Researchers will give the drug to 32 healthy volunteers from Caucasian, Japanese, and Chinese backgrounds to monitor for side effects and see how the body processes it. The st…

This study aims to measure how much of the medication bimekizumab (Bimzelx®) passes into breast milk. It will enroll 20 breastfeeding mothers who are already using this drug to treat conditions like psoriasis or arthritis. Researchers will collect breast milk samples over several…