Trevi Therapeutics
Clinical trials sponsored by Trevi Therapeutics, explained in plain language.
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New drug offers hope for stubborn cough sufferers
Symptom relief CompletedThis study tested a new tablet called nalbuphine ER to see if it can reduce coughing in people with refractory chronic cough (a cough that doesn't get better with treatment). 66 adults with this condition took the drug or a placebo for 21 days. The main goal was to measure how mu…
Phase: PHASE2 • Sponsor: Trevi Therapeutics • Aim: Symptom relief
Last updated May 22, 2026 14:05 UTC
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Healthy volunteers help test drug safety combo
Knowledge-focused CompletedThis study looked at how a long-acting painkiller (nalbuphine ER) interacts with two lung fibrosis drugs (pirfenidone and nintedanib) in 132 healthy adults. Researchers measured drug levels in the blood and checked for side effects. The goal was to see if these drugs can be safel…
Phase: PHASE1 • Sponsor: Trevi Therapeutics • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Liver function may change how itch drug works in body
Knowledge-focused CompletedThis early-phase study looked at how the drug nalbuphine extended-release is processed in people with mild, moderate, or severe liver problems compared to those with healthy livers. It also explored whether the drug could help relieve itching in participants who reported it. The …
Phase: PHASE1 • Sponsor: Trevi Therapeutics • Aim: Knowledge-focused
Last updated May 08, 2026 12:04 UTC