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New drug offers hope for stubborn cough sufferers

NCT ID NCT05962151

First seen Apr 02, 2026 · Last updated May 21, 2026 · Updated 11 times

Summary

This study tested a new tablet called nalbuphine ER to see if it can reduce coughing in people with refractory chronic cough (a cough that doesn't get better with treatment). 66 adults with this condition took the drug or a placebo for 21 days. The main goal was to measure how much their coughing decreased using a digital monitor. The study also checked for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accellacare North London

    Northwood, Middlesex, HA6 2RN, United Kingdom

  • Accellacare South London

    Orpington, Kent, BR5 3QG, United Kingdom

  • Accellacare Warwickshire

    Coventry, Warwickshire, CV3 4FJ, United Kingdom

  • Accellacare Yorkshire

    Shipley, Yorkshire, BD18 3SA, United Kingdom

  • Belfast City Hospital

    Belfast, Northern Ireland, BT9 7AB, United Kingdom

  • CIC Mauricie Inc.

    Trois-Rivières, Quebec, G8T 7A1, Canada

  • Egin Research Ltd

    High Wycombe, HP11 2QW, United Kingdom

  • Hull and East Yorkshire Hospitals NHS Trust - Castle Hill Hospital

    Cottingham, East Riding Of Yorkshire, HU16 5JQ, United Kingdom

  • Inspiration Research

    Toronto, Ontario, M5T 3A9, Canada

  • Kings College Hospital NHS Foundation Trust

    London, Greater London, SE5 9RS, United Kingdom

  • McMaster University Medical Centre

    Hamilton, Ontario, L8N 3Z5, Canada

  • North Tyneside General Hospital - Northumbria Healthcare NHS Foundation Trust

    North Shields, Tynemouth, NE29 8NH, United Kingdom

  • University Hospital of South Manchester NHS Foundation Trust (UHSM) - Wythenshawe Hospital

    Manchester, Greater Manchester, M23 9LT, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, West Midlands, B15 2GW, United Kingdom

Conditions

Explore the condition pages connected to this study.