Texas Tech University Health Sciences Center

This trial investigates whether sulforaphane, a nutrient found in broccoli, can reduce heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. About 70 participants will receive either sulforaphane or a placebo alongside their chemotherapy. The study m…

This study tests whether a supplement called geranylgeraniol (GG), derived from annatto seeds, can reduce muscle pain and weakness caused by statin medications. Researchers will give 95 adults either a low or high dose of GG or a placebo for three months. The goal is to see if GG…

This study looks at whether a single session of ultrasound-guided dry needling—inserting thin needles into tight neck muscles—can safely reduce headache symptoms. About 50 adults who have had headaches in the last 6 months and have tender neck muscles will participate. The goal i…

This study looks at whether eating pecans every day for three months can improve memory, mood, and brain function in people aged 50 and older with mild cognitive impairment. Sixty participants will be randomly assigned to eat either pecans or pretzels as a snack. Researchers will…

This study tests whether listening to a 30-minute audio track with special binaural beats (adjusted by brain activity) can reduce stress and improve thinking in 32 college music students preparing for a concert. Participants will have brain scans before and after listening to eit…

This trial compares two FDA-approved long-acting local anesthetics, Zynrelef and Exparel, for controlling pain after robotic sleeve gastrectomy. About 130 adults aged 18-65 scheduled for this surgery will receive one of the two drugs injected at the surgical site. Researchers wil…

This study tests whether a single dose of ketamine given during surgery can help adults with serious orthopedic trauma recover better. Researchers want to see if it reduces pain, lowers the need for opioids, and improves symptoms of depression and PTSD. Ninety participants will b…

This study tests whether using a blood flow restriction (BFR) cuff during physical therapy helps people recover better after ankle ligament reconstruction surgery. About 105 adults will be split into two groups: one gets standard therapy, the other adds BFR. Researchers will meas…

This pilot study is testing whether taking curcumin (the active ingredient in turmeric) for two weeks can cross into the brain and attach to amyloid beta proteins, which are linked to Alzheimer's disease. Researchers will use eye imaging to detect these proteins and also check ho…

This study is creating a data bank to better understand vaginal conditions like vulvodynia, yeast infections, bacterial vaginosis, and preterm labor. Researchers will look at proteins, immune markers, and vaginal bacteria in 550 women, including healthy volunteers and those with …