Takeda

This study tested a new drug called TAK-500, alone or with pembrolizumab, in 61 adults with advanced solid tumors like pancreatic, liver, and lung cancer. The goal was to check safety and see if the drug could shrink tumors. The trial was terminated early, so results are limited.

This study looked at the long-term safety of soticlestat, an add-on seizure medicine, in children and adults with severe epilepsy syndromes like Dravet and Lennox-Gastaut. Participants took soticlestat twice daily and visited the clinic every 2-6 months. The study was terminated …

This study tested a new drug called TAK-186 in adults with advanced head and neck, lung, or colorectal cancer that could not be removed by surgery. The main goal was to check for side effects and find the best dose. The trial was stopped early, and 95 people took part.

This study looked at whether adding ixazomib to lenalidomide and dexamethasone could help control multiple myeloma in people who had already received three cycles of a bortezomib-based treatment. About 141 adults took part. The goal was to see how long the disease stayed under co…

This study tested a stem cell injection called darvadstrocel to close complex anal fistulas in children with Crohn's disease. Participants first had surgery to clean the fistula, then received the injection. The study was terminated early after enrolling only 7 children, so resul…

This study looked at the long-term safety of soticlestat when added to standard seizure medicines for people with Dravet syndrome or Lennox-Gastaut syndrome. It included children and adults who had already been in earlier studies. The trial was stopped early, but researchers were…

This study tested the long-term safety and effectiveness of a repeat treatment called darvadstrocel in 53 adults with Crohn's disease and complex anal fistulas. Participants received one treatment and were monitored over several clinic visits, including MRI scans. The main goal w…

This study tested a new cell therapy called GDX012 in 16 people with acute myeloid leukemia that had come back or not responded to treatment. The main goals were to check safety and find the best dose. The trial was stopped early, but results help guide future research.

This study tested a drug called ponatinib, given with chemotherapy, for children and young adults up to age 21 with a specific type of leukemia (Ph+ ALL) that came back or didn't respond to other treatments. The goal was to find a safe dose and see if the cancer could go into rem…

This study tested a single dose of danavorexton in 41 adults with moderate to severe sleep apnea who were having abdominal surgery. The goal was to see if the drug could help them breathe steadily in the recovery room. The trial was stopped early, and results are not yet availabl…

This study tested a daily medicine called dexlansoprazole to heal and prevent return of esophagus damage in children aged 2 to 11 with erosive esophagitis. The medicine lowers stomach acid to allow the esophagus to heal. The study was stopped early, so results are limited.

This study looked at how the body absorbs, breaks down, and gets rid of the experimental drug subasumstat in adults with advanced solid tumors that had no other treatment options. Only 3 people took part before the study was stopped early. The main goal was to measure the drug an…