Stem cell shot for kids' Crohn's fistulas fizzles in early end
NCT ID NCT04701411
First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 29 times
Summary
This study tested a stem cell injection called darvadstrocel to close complex anal fistulas in children with Crohn's disease. Participants first had surgery to clean the fistula, then received the injection. The study was terminated early after enrolling only 7 children, so results are limited. The goal was to see if the fistula closed and stayed closed for up to a year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Amsterdam UMC, Locatie AMC
Amsterdam, 1105 AZ, Netherlands
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Erasmus Medisch Centrum
Rotterdam, 3000 CA, Netherlands
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Gabinet Lekarski Bartosz Korczowski
Rzeszów, 35-302, Poland
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Hadassah University Hospital-Mt. Scopus
Jerusalem, 9124001, Israel
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Hospital Infantil Universitario Nino Jesus
Madrid, 28009, Spain
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Hospital Materno-Infantil de Malaga
Málaga, 29011, Spain
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Hospital Sant Joan de Deu
Barcelona, 8950, Spain
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Hospital Universitari Germans Trias i Pujol
Badalona, 8916, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 8035, Spain
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Hospital Universitario Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Instytut "Pomnik - Centrum Zdrowia Dziecka"
Warsaw, 04-730, Poland
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Jichi Medical University Hospital
Shimotsuke-shi, 329-0498, Japan
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Juntendo University Hospital
Bunkyō City, 113-8431, Japan
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Medical Hospital, Tokyo Medical and Dental University
Bunkyō City, 113-8519, Japan
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Mie University Hospital
Tsu, 514-8507, Japan
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Miyagi Children's Hospital
Sendai, 989-3126, Japan
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Rambam Health Care Campus
Haifa, 3109601, Israel
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Schneider Children's Medical Center
Petah Tikva, 4920235, Israel
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Shaare Zedek Medical Center
Jerusalem, 91031, Israel
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Shamir Medical Center (Assaf Harofeh)
Be’er Ya‘aqov, 7033001, Israel
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Universitair Medisch Centrum Groningen (UMCG)
Groningen, 9713 GZ, Netherlands
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Uniwersytecki Szpital Dzieciecy w Krakowie
Krakow, 30-663, Poland
Conditions
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