State University Of New York At Buffalo

This study explores whether eating low-protein meals can make cancer immunotherapy more effective. Researchers will ask 30 adults with advanced solid tumors to follow a low-protein diet while receiving standard immunotherapy drugs. The main goal is to see if the diet is practical…

This study tests whether metformin, a common diabetes medication, is safe and can protect the brain in people aged 55-75 with multiple sclerosis (MS). Participants will take metformin or a placebo for 9 months, and researchers will use MRI scans to measure nerve health. The goal …

This study tests two different ways to help pregnant women stop using both cigarettes and e-cigarettes. Researchers will enroll 45 low-income pregnant women from Western New York who are currently using both products. Participants will be placed into one of three groups: quitting…

This study tests whether school-based health centers can help children with asthma from underserved communities get better care. About 400 kids with uncontrolled asthma will receive guideline-based checkups, daily preventive medication at school, and self-management support. The …

This study tests a program called CVD-FIT for African American adults who struggle to afford food and have heart disease risk factors. Participants get monthly income, weekly healthy food incentives, and phone coaching to reduce their heart risk. The goal is to see if this combin…

This study tests whether adding continuous glucose monitoring (CGM) to the standard Diabetes Prevention Program (DPP) helps adults with prediabetes stick with healthy habits and lower their risk of developing type 2 diabetes. Researchers will enroll 214 adults aged 18 and older w…

This pilot study looks at whether intermittent fasting (with an optional plant-rich diet) is practical for 30 men with prostate cancer who are receiving hormone therapy. Researchers will track how many patients stick with the diet and how it affects their cancer and side effects.…

This study tests a 24-week community program for adults aged 60 and older. Participants will do group art projects and play special exercise video games (SMARTfit) at the YMCA. The goal is to see if these activities improve thinking skills, balance, and overall quality of life. A…

This study tests whether a mild electrical current applied to the brain (tDCS) can improve movement and thinking in children aged 10-15 who had a mild concussion. Ten participants will receive the stimulation while researchers measure balance, coordination, and brain scans. The g…

This study tests whether toothbrushes with tapered bristles are better at removing plaque and reducing gum bleeding than standard round-end bristles. Researchers will also check if tapered bristles cause less gum scratching. About 70 adults with gum disease will use one of two to…

This study looks at whether a teacher-led program called the Early Childhood Friendship Project (ECFP) can help preschoolers reduce aggressive behavior and improve social and academic skills. About 600 children from diverse backgrounds will take part, and researchers will track c…

This pilot study looks at whether it's possible to track sleep and body clock rhythms in critically ill children ages 3 to 6 in the pediatric ICU. Researchers will use a watch-like device and saliva tests to measure sleep patterns. They will also test if giving bright light durin…

This study looks at whether patients in the ICU who need a breathing tube can keep getting nutrition right up until their tracheostomy surgery. The goal is to see if this approach helps them get more food without increasing the risk of food getting into their lungs or causing lun…

This study watches 250 children from BIPOC and low-income families to learn how their eating habits, physical activity, and decision-making change over three years. Researchers measure weight and body fat to see how these behaviors relate to health. No treatment is given—the goal…

This study tests a program called Military PAIRS, where Navy service members learn from a peer how to step in and prevent sexual violence and cut down on risky drinking. About 132 active-duty sailors who drink heavily will take part. Researchers will check if the program changes …

This study aims to find the best work and rest schedule for soldiers working in hot conditions, so they can finish missions faster without getting too hot or too tired. Researchers will test different work/rest cycles in 24 healthy, active adults to see how they affect body tempe…

This study looks at how food choices affect blood sugar control in 40 emergency medical workers who work night shifts. Participants will try a special diet to see if it helps keep their blood sugar stable. The goal is to learn if this approach is practical and helpful for shift w…

This study compares withdrawal symptoms in 370 daily vapers and cigarette smokers when they stop using nicotine for a short time. Researchers measure mood, cravings, sleep, and thinking skills to understand how people become dependent on e-cigarettes versus regular cigarettes. Th…

This study aims to find out if running a clinical trial remotely (from home) works as well as doing it in person. Researchers will compare how many people join and stay in the study, and how well they follow the treatment plan. About 200 adults who smoke will take part for 3 mont…

This study looks at how people with schizophrenia feel and perform when they stop using nicotine, either from vaping or smoking cigarettes. Researchers will measure mood, cravings, thinking skills, and eating habits in 64 participants. The goal is to understand withdrawal better …