Vaping vs. smoking: which is harder to quit?
NCT ID NCT05772845
First seen Mar 15, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This study looks at how daily vapers and cigarette smokers feel when they stop using nicotine for 24 hours. Researchers will measure withdrawal symptoms like mood changes, cravings, and attention problems in 370 participants. The goal is to understand nicotine dependence better and help create future treatments.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University at Buffalo
RECRUITINGBuffalo, New York, 14260, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could help develop better treatments for nicotine addiction by clarifying how withdrawal differs between vaping and smoking.
What could go wrong
This is an observational study, not a treatment trial. It measures symptoms but does not test a new therapy, so direct benefits are limited.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.