State University Of New York At Buffalo

This study is testing whether low-dose lithium aspartate, a dietary supplement, can slow the progression of Parkinson's disease. It involves 35 people who have already completed a lithium trial, and they will take lithium for another 24 weeks. Researchers will use brain scans and…

This trial tests whether providing monthly food vouchers for farmers markets and mailed food stock boxes, alongside diabetes education, can help African American adults with type 2 diabetes and food insecurity achieve better blood sugar control. Participants are randomly assigned…

This trial tests whether a 12-week program of physical therapy or home exercises can reduce pain and improve shoulder function in adults with glenohumeral arthritis, compared with no treatment. Participants are randomly assigned to one of three groups: supervised physical therapy…

This study looks at whether a drug called abaloparatide can improve bone quality in people with osteoporosis who need spine surgery. About 60 participants will take the drug for 3-6 months before and after surgery. The goal is to see if it reduces complications like broken hardwa…

This study tests whether giving financial incentives — including monthly cash, rewards for buying healthy food, and bonuses for lowering blood sugar — can improve diabetes control in adults who also struggle with food insecurity. Participants receive diabetes education and are ra…

This study tests whether a low dose of lithium (20 mg/day) can slow disease-related changes in the brain and blood of people with early-stage Parkinson's disease. Twenty participants will receive either lithium or a placebo for a period, and researchers will use MRI scans and blo…

This study tests whether adding two extra medications (semaglutide and dapagliflozin) to insulin helps adults with type 1 diabetes control their blood sugar better than insulin alone or with just one extra drug. The 78 participants, aged 18-70 with a BMI of 25 or higher, will be …

This study planned to test whether adding the antibiotic minocycline to standard stroke treatment could improve recovery in people who had a severe stroke. It was designed as a small, early-phase trial with about 40 participants, but it was withdrawn before enrolling anyone. Beca…

This study tests whether giving cash payments to inner-city African Americans with poorly controlled type 2 diabetes can improve their blood sugar levels and quality of life. Participants are randomly assigned to receive money for attending virtual diabetes education sessions or …

This study is creating a women-centered HIV prevention program for young women aged 18-35 in Ghana. The program uses WhatsApp and community workshops to provide information on HIV self-testing and PrEP, aiming to reduce stigma and increase prevention uptake. Researchers will test…

This study tests whether using a portable oxygen concentrator (a lightweight, battery-powered device) during walking or exercise helps people with interstitial lung disease (ILD) or COPD feel less breathless and be more active in their daily lives. Twenty-four participants will t…

This study is testing a 24-week community program for adults aged 60 and older. Participants will do weekly group exercise (using a SMARTfit system) and group art-making at a YMCA. Researchers want to see if this combination improves attention, balance, and the ability to do two …

This study tests whether a community-based music mindfulness program can reduce anxiety and depression in children aged 8-12 with ADHD or anxiety. Participants attend bi-weekly sessions for 8 weeks, wear fitness trackers, and complete surveys. The goal is to see if this approach …

This study looks at whether a group program combining visual art and exercise games can improve thinking, balance, and walking in older adults. About 80 participants with mild physical or cognitive issues will take part. The goal is to see if this fun, community-based approach he…

This study aimed to see if a corn-starch based drink taken before exercise could lower the risk of delayed low blood sugar in teens with type 1 diabetes. It also looked at whether it could improve biking performance. The study was withdrawn before enrolling any participants, so n…

This study compares two short-term pain relief methods for acute musculoskeletal injuries: a steroid dose pack (methylprednisolone) versus a combination of acetaminophen (Tylenol) and ibuprofen (Motrin). Sixty adults with new injuries (less than 2 weeks old) will take one of the …

This study looks at how not having reliable access to enough food might make it harder to lose weight. Researchers are giving 12 women who face food insecurity and have obesity and prediabetes a steady supply of healthy, low-calorie meals for a period. They will measure changes i…

This study tests whether doing clinical trial visits remotely (from home) works as well as coming into a clinic. About 200 adults will be randomly assigned to remote or in-person groups for intake and follow-up over 3 months. The goal is to see which method is better at keeping p…

This study follows 250 people who had a type of stroke called intracerebral hemorrhage (ICH) to understand why some experience progressive cognitive decline. Participants undergo advanced brain scans and tests of thinking and movement at 12–24 months after their stroke, with foll…

This study is observing up to 198 people with rapid-onset dystonia-parkinsonism (RDP) or related genetic mutations. Researchers aim to identify affected individuals, document how common the disease is, and track its progression over time. Participants undergo assessments of sympt…

This study looks at whether a special PET scan can help doctors better predict sudden cardiac arrest in people with heart failure and blocked arteries. About 300 participants who already have a defibrillator will be followed to see if heart nerve damage, heart size, or blood mark…

This study looks at why some people avoid information about colorectal cancer and tests a video designed to help them engage with it instead. About 1,500 adults aged 45 to 75 who are not up-to-date on screening will watch either the special video or a neutral one. Researchers wil…