Sheffield Children's Nhs Foundation Trust

Uveitis is an inflammation inside the eye that can cause permanent vision loss in children, often without symptoms. This study compares a high-resolution, non-contact eye scan called AS-OCT with the standard slit-lamp eye exam in 300 children aged 2 to 16 who attend a pediatric u…

This study tests a special MRI scan that uses xenon gas to find blockages in the lungs of children with protracted bacterial bronchitis (PBB), a condition causing a long-lasting wet cough. Current diagnosis often requires a bronchoscopy (camera in lungs under anesthesia) or a CT …

This study explores whether a special thermal camera can help doctors quickly detect infections in children's bones, joints, or soft tissues. About 30 children with suspected infections will have a 10-second video taken of the affected area to see if the heat pattern matches the …

This study compares two different doses of the steroid dexamethasone (0.3 mg/kg vs. 0.6 mg/kg) given by mouth to children aged 4-15 who come to the emergency department with an asthma attack. The goal is to see which dose works better at reducing the need for another steroid pres…

This pilot study is testing whether a combined PET-MRI scan can better detect if a child's brain tumor has returned after treatment. The study will include 5 children with high-grade gliomas or medulloblastomas who have unclear results from standard MRI. The main goal is to see i…