Shanghai Pharmaceuticals Holding Co., Ltd

This study tests a modified herpesvirus (T3011) combined with standard immunotherapy drugs (PD-1/PD-L1 inhibitors) in 68 people with advanced solid tumors that have not responded to other treatments. The goal is to see if the combination is safe and can shrink tumors or slow thei…

This study tests a new drug called LT3001 for people who have had a stroke caused by a blood clot. The goal is to see if it helps patients recover better and with fewer side effects. About 300 adults aged 18 to 80 will receive either the drug or a placebo within 24 hours of their…

This study tests a new drug called SPH4336 combined with hormone therapy for people with a type of breast cancer (HR-positive, HER2-negative) that has spread to the brain. The goal is to see if the combination can shrink or control brain tumors. About 52 adults with advanced dise…

This study tests a new drug called SPH4336, given alone or with another drug called cadonilimab, in people with advanced solid tumors (including a type of liposarcoma). The goal is to see if the treatment can shrink tumors or slow their growth. About 63 participants will take par…

This study is testing an experimental drug called B001 in people with a specific form of NMOSD, a rare disease where the immune system attacks the optic nerves and spinal cord. The main goal is to check the drug's safety and how the body processes it. About 45 adults who have had…

This study tests a new drug called SPH4336 combined with hormone therapy for people with a certain type of advanced breast cancer (HR-positive, HER2-negative) that has gotten worse after standard treatment. About 254 participants will receive the combination to see if it shrinks …

This early-phase study tests an experimental tablet called SPH5030 in 150 adults with advanced HER2-positive solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the best dose, and measure how the body processes it.…

This study tests a new drug, T3011, in 42 people with advanced melanoma that has spread. The main goals are to check safety and see if tumors shrink. Participants must have measurable tumors and be well enough for daily activities. This is an early-phase trial, so the focus is on…

This early-stage study tests whether the experimental drug SPH9788 is safe and tolerable in healthy adults aged 18 to 45. About 94 participants will receive either the drug or a placebo, and researchers will monitor for side effects and how the drug moves through the body. The go…

This early-stage study tests the safety of a new drug called SPH7854 in 111 healthy adults. Researchers will monitor for side effects and measure how the drug moves through the body. This study does not aim to treat any disease, but the results will help guide future research for…