Seattle Children's Hospital

This early-stage trial tests a new treatment for adults with solid tumors that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to better recognize and attack cancer cells that carry a protein called GPC3. The…

This study tests whether a short, structured team huddle before each soccer game can improve how often young athletes report possible concussions. Researchers will include 2,000 children aged 9-13 and their coaches. The goal is to see if this simple, repeatable conversation can m…

This study looks at whether using clear, non-blood fluids to fill the heart-lung machine during surgery can reduce inflammation in infants having a hole in the heart repaired. Sixty babies aged 1 to 18 months will be enrolled. Researchers will measure inflammation markers and rec…

This study tests a training program called PIVOT-IN that teaches hospital doctors and nurses how to talk with families about childhood vaccines. The goal is to see if this training helps more kids get the vaccines they need while they are in the hospital. About 2,000 children and…

This study tracks 500 people who have received or will receive gene therapy products from Seattle Children's Therapeutics. The goal is to watch for any long-term side effects over up to 15 years. Participants will have regular check-ups and lab tests, but no new treatment is give…

This study tests whether a website called the Family Safety Check-In can help families with children store their firearms more safely. About 548 parents or guardians who have guns at home and currently store them unsafely will be randomly assigned to use the website or not. The g…

This study looks at how two types of birth control devices—copper IUDs and hormonal IUDs—affect the bacteria in the vagina and the risk of infections. About 120 HIV-negative women aged 18-40 will be randomly assigned to one device and followed for a year. Researchers will collect…