Ruijin Hospital

This early-stage study tests a new medicine called GB261 in 10 people with systemic sclerosis, a disease that causes skin thickening and organ damage. The main goal is to check safety and how the body handles the drug. Participants must have moderate to severe skin involvement an…

This early-phase study tests a new drug, cizutamig, in 10 adults with systemic sclerosis, a condition that causes skin hardening and organ damage. The main goal is to check if the drug is safe and tolerable. Researchers will also look at how the body processes the drug and whethe…

This study tests a new drug (QL1706) combined with chemotherapy for people with a type of esophageal cancer that is hard to remove surgically. About 24 participants will receive the treatment before surgery, and then continue with the new drug afterward. The goal is to see if thi…

This study tests a new drug (BEBT-908) combined with chemotherapy in adults with a rare, high-risk form of acute lymphoblastic leukemia (ALL) that has a specific gene change (MEF2D rearrangement). Participants are in remission but still have tiny amounts of cancer cells detectabl…

This study is for people with stomach or gastroesophageal junction cancer that has spread to the lining of the abdomen (peritoneal metastasis). It tests whether adding the drug SHR-1701 to chemotherapy can help patients live longer and possibly become candidates for surgery. Abou…

This study tests a new combination of two powerful immune-based treatments—glofitamab and CAR-T therapy—for people with high-risk large B-cell lymphoma that has come back or not responded to prior treatment. The goal is to see if the combination can shrink or eliminate tumors mor…

This study tests a new drug called cadonilimab combined with radiation therapy for people with advanced cervical cancer who cannot receive standard chemotherapy due to age or health issues. The goal is to see if this combination can make the cancer disappear completely. About 45 …

This early-phase study tests a combination of three drugs (sonrotoclax, zanubrutinib, and obinutuzumab) as a first treatment for people newly diagnosed with an aggressive form of mantle cell lymphoma. About 28 adults with high-risk features will receive the therapy to see how man…

This study will test a new type of PET scan that looks for a protein called Claudin18.2 on cancer cells in people with pancreatic or stomach cancer. The goal is to see if this scan can accurately find which tumors have this protein, helping doctors choose the right targeted thera…

This study tests a special baby formula made with broken-down whey protein to see if it can ease mild allergy symptoms like skin rashes or tummy troubles. About 160 infants with mild allergies will be randomly assigned to get either this special formula or a standard one. The mai…

This study will collect blood and sputum samples from 411 adults with acute respiratory distress syndrome (ARDS) who are on a breathing machine. Researchers will analyze the samples to find patterns in genes, bacteria, and metabolites that may predict how well patients respond to…

This study looks at whether an ultrasound-based risk score can better predict pressure injuries (bedsores) in critically ill patients than current methods. In the first phase, researchers will check how accurate the score is. In the second phase, some patients will get special ca…