Ruijin Hospital

This study tests a combination of two drugs (orelabrutinib and rituximab) in people newly diagnosed with a slow-growing type of mantle cell lymphoma. Some participants may also receive a stem cell transplant using their own cells. The goal is to see how well the treatment shrinks…

This early-phase study tests a new treatment called RXIM002 for people with severe autoimmune diseases that haven't responded to standard therapies. RXIM002 uses circular RNA to create CAR T-cells inside the body that target and destroy faulty B-cells. The main goals are to check…

This early-phase study tests a new mRNA-based drug (ABO2203) designed to help control autoimmune diseases that haven't responded to standard treatments. About 66 adults with conditions like lupus or rheumatoid arthritis will receive the therapy to see if it is safe and shows sign…

This study tests a combination of three drugs (cadonilimab, LM-302, and S-1) given through a vein plus a chemotherapy drug (paclitaxel) infused directly into the abdomen. It is for people with a specific type of advanced stomach cancer (Claudin 18.2-positive) that has spread to t…

This study tests a combination of three drugs (orelabrutinib, lisaftoclax, and rituximab) in 25 people with high-risk mantle cell lymphoma who have never been treated. The goal is to see how many patients achieve complete remission and how long the benefits last. Researchers will…

This study tests whether a donor stem cell transplant can keep high-risk acute myeloid leukemia (AML) from coming back. About 90 newly diagnosed patients with specific genetic markers will receive the transplant after standard chemotherapy. Researchers will track how long patient…

This study is testing a new type of PET scan tracer (68Ga-FAPI) to see if it can better detect lung scarring and kidney problems in people with ANCA-associated vasculitis. The tracer targets specific cells linked to tissue damage, allowing a whole-body scan in one session. Resear…

This study follows 640 participants—including people with Parkinsonism, those with REM sleep behavior disorder, and healthy volunteers—over 5 years. Researchers use brain scans, movement tests, and biological samples to track how the disease changes over time and to improve diagn…

This study is creating a detailed database of 700 people with Parkinson's disease or multiple system atrophy in Shanghai. Researchers will collect medical history, run tests, take brain scans, and track changes over time. The goal is to find early signs of disease, improve diagno…

This study checks if an AI-driven robot can safely and independently guide a bronchoscope to lung nodules in 20 patients. The robot uses artificial intelligence to register the lung map without manual adjustments. Researchers will measure how often the AI succeeds on its own, how…