Royal North Shore Hospital

This study is for men whose prostate cancer has returned years after their first radiation treatment. It tests whether a second, highly focused dose of radiation (called SBRT) can be given safely to control the cancer. The main goal is to see how much radiation can be given witho…

This study compares a single, higher-dose radiation treatment to the usual 5-10 sessions for people with cancer that has spread. The goal is to see if one session can provide longer-lasting relief from symptoms like pain. About 100 participants will be followed for up to a year t…

This study tests a new radiation technique called adaptive radiotherapy for prostate cancer. It adjusts the radiation beam each day to match changes in the body, which may allow doctors to use smaller treatment margins and reduce side effects. The study has two phases: first, to …

This study tests a new type of radiation therapy that adjusts to daily changes in a patient's body shape. The goal is to see if this approach can safely reduce side effects for people with pelvic cancers like prostate, bladder, rectal, or gynecological cancers. About 280 particip…

This study tests whether artificial intelligence (AI) can help doctors outline the area to be treated with radiation for breast cancer. The goal is to see if AI-assisted outlining is as good as the current manual method and if it saves time. About 444 adults with breast cancer wi…

This study tests whether 3D-printed custom applicators can deliver radiation more precisely than standard cylinder applicators for gynecologic cancers like endometrial, vaginal, and vulvar cancer. Ten participants will receive brachytherapy with a personalized 3D-printed mold. Th…