Pontificia Universidad Catolica De Chile

This study compares two ways of positioning patients with severe lung failure (ARDS) who are on a breathing machine: lying face-down for more than 48 hours straight versus 16-24 hours daily. The goal is to see which approach reduces deaths and causes fewer complications. About 78…

This study tests whether taking a daily oil rich in linoleic acid (an omega-6 fat) for 8 weeks can improve insulin resistance in adults aged 20-60 who already have this condition. Participants will be randomly assigned to receive either the linoleic acid oil or a control oil, whi…

This study tests whether adding photosynthetic microalgae to a skin regeneration scaffold helps deep wounds heal faster and with fewer infections. Twenty adults with full-thickness skin wounds will receive either a standard scaffold or one containing algae. The goal is to see if …

This study tests whether giving tuberculosis (TB) preventive medicine right away to children and teens who live with a TB patient can prevent them from getting infected. About 647 participants aged 5 to 17 will either get immediate treatment or standard care. The goal is to see i…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks and diagnosed with apnea of prematurity will take part. Each baby will be monitored for 48 hours with the device and …

This study tests an AI system that helps anesthesiologists give the right amount of pain medicine during surgery. The goal is to avoid giving too much or too little painkiller, which can cause side effects or discomfort. About 150 adults having planned surgeries will take part, a…

This study tests whether a personalized, algorithm-based psychotherapy is more effective than usual one-on-one therapy for adults with major depression complicated by personality problems or past trauma. About 150 people in Chile's public mental health system will be randomly ass…

This study tests whether using a virtual reality headset during exercise can reduce the effort it takes to breathe. Ten healthy adults will cycle with and without VR to see if it lowers breathing strain and anxiety. The goal is to gather early evidence for a possible non-drug way…

This study looks at how changing the pressure in a breathing machine (ventilator) affects the effort patients need to breathe on their own. It will include 12 adults in the ICU who are already using a ventilator to help them breathe. Researchers will test four different pressure …