Pakistan Institute Of Medical Sciences
Clinical trials sponsored by Pakistan Institute Of Medical Sciences, explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- Could a common asthma drug shorten bronchiolitis hospital stays? Results expected Sep 2026 (estimated)
- Can a lower dose of acne drug work just as well with fewer side effects? Results expected Oct 2026 (estimated)
- Tooth study tests which root canal prep is more accurate Results expected Oct 2026 (estimated)
- New psoriasis cream takes on old standby in Head-to-Head trial Results expected Oct 2026 (estimated)
- Braces patients get AI coach: chatbot may beat pamphlets for cleaner teeth Results expected Nov 2026 (estimated)
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Head-to-Head: which drug tames mania best?
Disease control Not yet recruitingThis study compares two approved antipsychotic drugs, risperidone and cariprazine, in 50 adults with bipolar 1 disorder experiencing acute mania. Participants take one of the drugs for 6 weeks, and doctors measure how well symptoms improve using a standard mania rating scale. The…
Phase 4 • Sponsor: Pakistan Institute of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can a lower dose of acne drug work just as well with fewer side effects?
Disease control Not yet recruitingThis study tests whether a low daily dose of the acne drug isotretinoin can clear moderate to severe acne as effectively as the standard dose, but with fewer side effects. About 164 people aged 18-45 will be randomly assigned to one of two dose groups. Researchers will track acne…
Phase 4 • Sponsor: Pakistan Institute of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New psoriasis cream takes on old standby in Head-to-Head trial
Disease control Not yet recruitingThis study will test whether a newer cream called tapinarof works better than the standard betamethasone cream for mild-to-moderate plaque psoriasis. About 120 adults will use one of the two creams daily for up to 12 weeks. The main goal is to see how many people get at least a 7…
Phase 4 • Sponsor: Pakistan Institute of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Heart rehab at home: a new hope for patients in Low-Resource areas?
Symptom relief Not yet recruitingThis study tests whether a home-based cardiac rehabilitation program can improve quality of life and health behaviors in heart patients living in low-resource settings in Pakistan. The program includes diet advice, exercise suggestions, medication reminders, and counseling, deliv…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Tooth study tests which root canal prep is more accurate
Knowledge-focused Not yet recruitingThis lab study compares two ways to prepare a root canal before cleaning it: using hand files or a mechanical rotary tool. Researchers will test 60 extracted single-rooted teeth to see which method keeps the working length more accurate. The goal is to improve root canal success,…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Can a better rinse reach the root's tip? a tooth study puts three irrigation methods to the test.
Knowledge-focused Not yet recruitingThis trial compares three root canal irrigation methods—conventional needle, side-vented needle, and ultrasonic activation—to see which one best delivers cleaning fluid to the very tip of the root. Using extracted single-rooted premolars, researchers will measure how far a dye-mi…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Which chest tube closure method wins? study aims to find out.
Knowledge-focused Not yet recruitingThis study compares two techniques for closing the wound after a chest tube is removed: the purse-string suture and the plug method. Researchers want to see which one leads to better healing, fewer complications like air leaks or infections, and higher patient satisfaction. About…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New coating for root canal fillings may reduce leakage
Knowledge-focused Not yet recruitingThis lab study will test 60 extracted human teeth to see if a special coating on gutta-percha (the material used to fill root canals) helps create a tighter seal compared to standard gutta-percha. Both groups will use the same bioceramic sealer. The goal is to find which combinat…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC