Otsuka Pharmaceutical Co., Ltd.

This study followed 1,802 people in Japan with autosomal dominant polycystic kidney disease (ADPKD) who were taking the drug tolvaptan. Researchers wanted to see how safe and effective the drug is in everyday medical practice, not just in controlled trials. They measured changes …

This study tested a daily pill called ETC-1002 in 130 adults with high LDL cholesterol who either couldn't take statins or needed extra help. Over 52 weeks, the drug lowered LDL cholesterol and other harmful fats. The main goal was to check safety and how well the drug works long…

This early-phase study tested a new drug (OPB-111077) combined with two standard chemotherapy drugs (bendamustine and rituximab) in 36 adults with diffuse large B-cell lymphoma that had come back or stopped responding to treatment. The main goal was to check the safety and tolera…

This study tested an experimental drug called OPC-131461 in 157 adults with heart failure who still had swelling (edema) despite taking standard water pills. The goal was to see if the drug could help reduce body weight by removing extra fluid. Participants received either a plac…

This study tested whether eating food changes how the body absorbs a new once-weekly version of the schizophrenia drug brexpiprazole. Fifty-nine adults with stable schizophrenia took the drug once with food and once without food, and researchers measured drug levels in their bloo…