Nrg Oncology

This study is testing a personalized approach to treat nasopharyngeal cancer, a type of throat cancer linked to the Epstein-Barr virus. All participants first receive standard radiation and chemotherapy. Afterward, a blood test checks for traces of the virus. Based on the result,…

This study is testing if giving a higher, more focused dose of radiation, or using a different type called proton therapy, helps people with a newly diagnosed aggressive brain tumor (glioblastoma) live longer than the standard radiation dose. All participants also receive the sam…

This large study aims to personalize treatment for men with high-risk prostate cancer. Based on a genetic test score, patients receive either a shorter course of hormone therapy (to reduce side effects) or a stronger hormone therapy regimen (to better control aggressive cancer), …

This study compares two types of radiation therapy for patients with liver cancer that cannot be removed by surgery. Researchers want to see if proton therapy, which can target tumors more precisely, helps patients live longer with fewer side effects than standard photon radiatio…

This study aims to find out if a daily hormone pill (letrozole) works as well as or better than standard chemotherapy (paclitaxel/carboplatin) followed by the same pill for patients with advanced low-grade ovarian, fallopian tube, or peritoneal cancer. It involves 450 women who h…

This study aims to find out if giving a common chemotherapy drug (cisplatin) weekly alongside radiation is easier for patients to tolerate than giving it every three weeks. It will also check if the weekly schedule is at least as good at helping patients live longer. The trial in…

This study compares two radiation therapy methods for men with intermediate-risk prostate cancer that hasn't spread. It tests whether a shorter, more precise treatment (SBRT) given in 5 sessions causes fewer side effects and works as well as the standard longer treatment (IMRT) g…

This study is for men whose prostate cancer has returned after surgery. It tests if adding a drug called apalutamide to standard radiation therapy works better than radiation alone to keep the cancer from progressing. Apalutamide works by blocking hormones that can fuel prostate …

This study compares two treatment schedules for patients with cancer that has spread to the brain. All patients receive surgery and a precise, high-dose radiation treatment called stereotactic radiosurgery (SRS). The trial is testing whether giving the radiation treatment before …

This early-stage study is testing the safety of adding a specially designed virus (OBP-301) to standard chemotherapy and radiation for patients with advanced esophageal or gastroesophageal cancer who are not candidates for surgery. The virus is meant to infect and kill cancer cel…

This study is testing if adding a second chemotherapy drug, lomustine, to the current standard treatment helps people with a newly diagnosed, aggressive brain tumor live longer. It is for adults aged 18-70 with a specific tumor type (MGMT methylated glioblastoma) who have not had…

This trial is for people with advanced non-small cell lung cancer that has spread to only a few other body sites. It tests whether adding targeted radiation or surgery to the areas where cancer remains, on top of ongoing maintenance chemotherapy, helps control the cancer better a…

This study aims to find a better way to calculate the right dose of the chemotherapy drug carboplatin for cancer patients. Researchers are testing if a special dye (iohexol) can help doctors measure kidney function more accurately than standard blood tests, which is key for safe …