Nottingham University Hospitals Nhs Trust

This study explores whether a short-term low-energy diet (using meal replacements) can help adolescents aged 12–17 with obesity and type 2 diabetes lose weight and potentially achieve diabetes remission. Participants follow the diet for 12 weeks, then gradually reintroduce food o…

This study is testing whether a quick, at-home stool test (FIT) can accurately detect if bowel cancer has returned after surgery. About 1,000 patients who are due for a routine colonoscopy will also provide a FIT sample. If the test works well, some patients might be able to skip…

This study works to prevent pressure injuries (bedsores) in hospitalized children and young people up to age 19. Researchers will improve a risk assessment tool to work better for those with dark skin tones. About 542 participants across 10 UK hospitals will help test the updated…

Falls are common among older people in care homes and can cause serious injury. After a fall, residents often need quick checks and coordinated support from several health and social care organisations, but those groups may work differently. Researchers are running a study with c…

This study follows 100 people with multiple sclerosis who had a special MRI scan years ago. Researchers will take blood samples and offer a new MRI to see if iron rims around brain lesions are linked to worsening disability. They also want to find genetic factors that might cause…

This study tests a new 3D visualization tool called vEUA that helps surgeons see fistulas more clearly before operating on people with perianal Crohn's disease. About 30 adults who need surgery for fistulas or abscesses will be randomly assigned to standard care or care with the …