Poo test could spare thousands from unpleasant camera exams
NCT ID NCT06689293
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a quick, at-home stool test (FIT) can accurately detect if bowel cancer has returned after surgery. About 1,000 patients who are due for a routine colonoscopy will also provide a FIT sample. If the test works well, some patients might be able to skip the colonoscopy in the future.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Eligible patients, due to have their 3-year postoperative surveillance colonoscopy/CTC, at each site will be invited to participate in the study. The colorectal cancer lead in each Trust has agreed to support the study and actively recruit from their site. Patients will be identified at each site by the clinical teams based there. Each trust has a locally managed electronic database used to manage surveillance scheduling of investigations for patients following CRC surgery. Participating Trusts include Nottingham University Hospitals \[NUH\], Royal Derby Hospitals \[RDH\], Chesterfield Royal Hospital Foundation Trust \[CRHFT\], Sherwood Forest Hospitals NHS Foundation Trust \[SFHFT\], United Lincolnshire Hospitals Trust \[ULHT\], University Hospitals of Leicester NHS Trust \[UHLT\] and Northampton General Hospital NHS Trust \[NGHT\].
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Histological diagnosis of colorectal carcinoma * Previously treated by surgical resection with curative intent for colorectal carcinoma * Due whole-colon investigation for CRC follow-up as part of local routine care (Colonoscopy or CT colon) Exclusion Criteria: * Patients under the age of 18 * Patients unable to give valid informed consent * Patients with a current ileostomy, or no remaining colon after their operation (patients with colostomy will not be excluded) * Patients already diagnosed with recurrence of their colorectal cancer
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Nottingham University Hospitals NHS Trust
RECRUITINGNottingham, NG7 2UH, United Kingdom
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