National Heart, Lung, And Blood Institute (nhlbi)
Clinical trials sponsored by National Heart, Lung, And Blood Institute (nhlbi), explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- New heart signal recorder aims to sharpen procedure accuracy Results expected Nov 2026 (estimated)
- CLL drug venetoclax under the microscope: genetic clues may improve treatment Results expected Nov 2026 (estimated)
- New heart procedure aims to zap stubborn arrhythmias Results expected Dec 2026 (estimated)
- Where you live could impact your heart, study says Results expected Dec 2026 (estimated)
- DC churches partner with NIH to tackle heart health in black communities Results expected Dec 2026 (estimated)
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Can a catheter slice thick heart muscle without open surgery?
Disease control Not yet recruitingThis study tests a minimally invasive procedure called SESAME for people with thickened heart muscle that blocks blood flow from the heart. The procedure uses a catheter to make a controlled slice in the muscle, aiming to relieve symptoms like shortness of breath. Researchers wil…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Sep 21, 2026 21:00 UTC
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Can a new pill outsmart Drug-Resistant leukemia?
Disease control Not yet recruitingThis phase 2 trial tests an oral drug called nemtabrutinib in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has stopped responding to other targeted therapies. Participants take nemtabrutinib once daily in 28-day cycles until the …
Phase 2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Sep 21, 2026 21:00 UTC
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Super-Resolution heart scans: sharper images without extra radiation?
Knowledge-focused Not yet recruitingThis study will take standard heart CT scans from 1000 adults with structural heart disease and use a super-computer to create ultra-high-resolution images. The goal is to see if these enhanced images show more detail than the originals. No new treatments are being tested; it's a…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 21, 2026 21:00 UTC
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Fatty meals may trap vitamin e in the blood, study suggests
Knowledge-focused Not yet recruitingThis study investigates how eating three high-fat meals in a row changes vitamin E levels in the blood. Researchers will compare people with normal blood fats to those with high blood fats (hyperlipidemia). The goal is to understand whether fats in the blood can trap vitamin E, p…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 21, 2026 21:00 UTC
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Can tracking immune chaos in sepsis reveal new treatment targets?
Knowledge-focused Not yet recruitingSepsis happens when the body's immune response spirals out of control, damaging organs and causing about 1 in 5 deaths worldwide. This study follows 500 adults hospitalized with sepsis to track how their immune systems change over time. Researchers will collect blood samples and …
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC