Madrigal Pharmaceuticals, Inc.

This study tested an experimental drug called MGL-3196 in 116 adults with heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes very high cholesterol. Participants took either the drug or a placebo daily for 12 weeks. The main goal was to see if th…

This study tested an oral drug called MGL-3196 in 125 adults with NASH, a serious liver disease. The main goal was to see if the drug could reduce liver fat measured by MRI after 12 weeks, compared to a placebo. Results suggest the drug may help control the disease, but long-term…

This study looked at how the drug resmetirom is processed in people with severe kidney impairment compared to healthy people. 28 participants took 100 mg of resmetirom daily for 6 days. The goal was to measure drug levels in the blood and check for side effects, helping doctors u…