New pill shows promise for inherited high cholesterol
NCT ID NCT03038022
First seen Jan 04, 2026 · Last updated Jun 19, 2026 · Updated 18 times
Summary
This study tested an experimental drug called MGL-3196 in 116 adults with heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes very high cholesterol. Participants took either the drug or a placebo daily for 12 weeks. The main goal was to see if the drug could lower LDL (bad) cholesterol more than placebo. The study is complete, and results focus on cholesterol changes and safety.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Madrigal Research Site
Aalborg, Denmark
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Madrigal Research Site
Copenhagen, Denmark
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Madrigal Research Site
Esbjerg, Denmark
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Madrigal Research Site
Herlev, Denmark
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Madrigal Research Site
Viborg, Denmark
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Madrigal Research Site
Amsterdam, Netherlands
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Madrigal Research Site
Apeldoorn, Netherlands
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Madrigal Research Site
Goes, Netherlands
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Madrigal Research Site
Hoorn, Netherlands
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Madrigal Research Site
Nijmegen, Netherlands
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Madrigal Research Site
Zwijndrecht, Netherlands
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Madrigal Research Site - 1
Oslo, Norway
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Madrigal Research Site - 2
Oslo, Norway
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.