King Edward Medical University

This study follows 1,500 adults with focal-onset seizures who take eslicarbazepine as part of their normal care. Researchers track changes in seizure frequency, quality of life, and side effects over three months. Participants include people newly diagnosed and those switching fr…

This trial tests whether adding N-acetylcysteine (NAC) to standard care improves survival in adults with acute liver failure not caused by acetaminophen. Sixty-two patients will be randomly assigned to receive NAC or standard care alone. The study tracks survival at 28 days, hosp…

This Phase 3 trial compares a modified version of the standard DHAP chemotherapy regimen against the original in adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The modified regimen spreads out the cisplatin and cytarabine doses over several days, aiming…

This study compares two surgical techniques for treating carbuncles (large, deep skin infections) in people with diabetes aged 25 to 70. One method uses a cross-shaped cut to drain the infection, while the other removes more tissue. Both are followed by a vacuum device to help he…

This study compares two minimally invasive surgical techniques—ETEP and SCOLA—for repairing paraumbilical hernias (belly button hernias). Researchers will randomly assign 86 adults to receive one of the two procedures and track outcomes like surgery time, pain, infections, and fl…

This study tests whether vonoprazan, a stomach acid blocker, can prevent ulcers that often form after endoscopic variceal band ligation (EVBL) in people with liver cirrhosis. About 154 adults will take either vonoprazan or a placebo daily for 14 days after the procedure. Research…

This study compares two methods of removing the gallbladder during laparoscopic (keyhole) surgery: through a port near the belly button or one below the breastbone. The goal is to see which approach causes less pain and fewer wound problems like infection. The trial will involve …

This study compares aloe vera gel dressings to standard paraffin-based dressings for pain relief at the donor site after skin graft surgery. About 72 adults aged 18-60 will receive one of the two dressings, and their pain will be measured on day 7 using a standard pain scale. The…

This study compares two ointments—lignocaine and glyceryl trinitrate (GTN)—for pain relief after hemorrhoid removal. Sixty-four adults will apply one of the ointments three times daily after surgery. Researchers will measure pain scores, wound healing time, and patient satisfacti…

This study looks at whether giving less IV fluid after gallbladder removal is as safe and effective as giving more. About 380 adults having planned laparoscopic gallbladder surgery will be randomly assigned to receive either liberal or restricted fluids for 6 hours after the oper…