Johns Hopkins University
Clinical trials sponsored by Johns Hopkins University, explained in plain language.
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New study aims to boost HIV care for drug users in india
Disease control OngoingThis study looks at three strategies to help people who inject drugs in India control their HIV: starting treatment the same day, receiving care at community centers instead of government clinics, and getting extra support if the first treatment doesn't work. About 800 participan…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Balloon in the womb: new hope for babies with rare birth defect
Disease control OngoingThis study tests a procedure called FETO for unborn babies with a severe form of left congenital diaphragmatic hernia (CDH), a birth defect where the diaphragm doesn't form properly, causing organs to move into the chest and compress the lungs. The procedure involves placing a ti…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Zapping the brain to lift Parkinson's depression
Symptom relief TerminatedThis study tests whether a gentle brain stimulation technique called tDCS can improve depression and other non-motor symptoms in people with Parkinson's disease. About 80 participants will receive either real or fake stimulation over 10 sessions. The goal is to see if this safe, …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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Can a simple blood test predict liver cancer's return?
Knowledge-focused OngoingThis study collects blood and tumor tissue from 360 early-stage liver cancer patients who had surgery to remove their cancer. Researchers look for specific immune system markers and antibodies that might signal whether the cancer will come back. The goal is to better understand w…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Brain zaps reveal secrets of aging and awareness
Knowledge-focused OngoingThis study looks at how aging changes our ability to become aware of patterns during a simple learning task. Researchers used a mild electrical current on the scalp to temporarily disrupt a brain area in 16 healthy adults aged 20-30. They then measured awareness of a tone-air puf…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Drug demand study in healthy volunteers withdrawn before starting
Knowledge-focused TerminatedThis study was designed to see how different drugs and drug combinations change mood, pain tolerance, and mental performance in healthy adults aged 18 to 55. Researchers planned to measure how much of a blinded drug people would take when it was free, and the highest price they w…
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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Could your anesthesia choice prevent a deadly complication during hip surgery?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether the type of anesthesia (general vs. spinal) affects the risk of bone cement implantation syndrome (BCIS) in 24 adults having hip fracture surgery. BCIS can cause dangerous drops in blood pressure and oxygen levels. The goal is to see if spinal anesthes…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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Broccoli extract tested as Anti-Aging skin treatment
Knowledge-focused OngoingThis small early-phase study at Johns Hopkins University is testing whether a cream made from sulforaphane, a compound found in broccoli, can improve skin aging and protect against damage from ultraviolet (UV) and visible light. Twelve adults with healthy or moderately aged skin …
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC