Irccs Policlinico S. Donato

This study tests whether a gel called Prontosan Wound Gel X, applied during heart surgery, can lower the chance of wound infections. About 456 adults having planned heart surgery at one Italian hospital will take part. The gel is already used in practice, and researchers will tra…

This study tests whether giving women the full recommended doses of heart failure medications quickly after a hospital stay can reduce the risk of death or readmission within a year. About 360 women from 13 Italian hospitals will be randomly assigned to either intensive medicatio…

This study enrolls 20 adults with COL5A gene mutations to explore why some develop aortic aneurysms and others do not. Researchers will take a small skin sample and study the cells to compare collagen production and tissue structure. The goal is to find biological clues that coul…

This study aims to find out if people with metastatic breast or colon cancer produce antibodies that might also attack the heart, potentially causing dangerous heart rhythms. Researchers will test blood samples from 196 participants at the start of the study and again after 6 and…

This study aims to understand bone mineralization and fracture risk in people with Marfan or Ehlers-Danlos syndrome. Researchers will review existing medical records and bone density scans from 150 patients. The goal is to identify patterns of bone loss and osteoporosis over time…