Ionis Pharmaceuticals, Inc.

This study looked at the safety and effectiveness of a drug called donidalorsen for people with hereditary angioedema (HAE), a condition that causes sudden, severe swelling. Twenty participants who completed a previous study received the drug for up to 64 weeks. The main goal was…

This early-stage study tested a new drug called BIIB094 in 62 adults with Parkinson's disease. The main goal was to see if the drug is safe and tolerable when given as a shot into the spine. Researchers also looked at how the drug moves through the body. This study is now complet…

This study tested a new medicine called olezarsen in 446 adults with very high levels of triglycerides (a type of fat in the blood). Participants received either the drug or a placebo as a shot under the skin. The main goal was to see if olezarsen could safely lower triglyceride …

This study tested an experimental drug called olezarsen in 154 adults with high triglycerides (a type of fat in the blood) and either heart disease or very high triglycerides. The goal was to see if the drug could safely lower triglyceride levels more than a placebo over 6 and 12…

This study tested a new medicine called olezarsen in about 1,500 adults with very high triglycerides (a type of blood fat) and either heart disease or high risk for it. The goal was to see if olezarsen could lower triglyceride levels more than a placebo over 25 weeks. Participant…

This study tested a new medicine called olezarsen in 617 adults with severely high triglycerides, a type of blood fat that raises the risk of heart problems and pancreatitis. Participants received either the drug or a placebo as a shot under the skin. The main goal was to see if …