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Heart scans track protein buildup in rare disease

NCT ID NCT06073574

First seen Jan 06, 2026 · Last updated May 20, 2026 · Updated 24 times

Summary

This study uses MRI scans to measure amyloid protein buildup in the hearts of up to 150 people with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM). Participants are already enrolled in a larger treatment study. The goal is to see how the amyloid burden changes over time, helping researchers better understand the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Azienda Ospedale Università di Padova

    Padova, 35128, Italy

  • Azienda Ospedaliero - Universitaria Careggi

    Florence, 50139, Italy

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Hospital Universitario Puerta de Hierro

    Majadahonda, 28222, Spain

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Richmond Pharmacology

    London, SE1 1YR, United Kingdom

  • Royal Free London NHS Foundation Trust

    London, NW3 2QG, United Kingdom

  • Synexus - Manchester Clinical Research Centre

    Manchester, M15 6SE, United Kingdom

  • Synexus - Scotland Clinical Research Centre

    Bellshill, ML4 3NJ, United Kingdom

  • Synexus - Wales

    Cardiff, CF15 9SS, United Kingdom

  • Synexus Midlands Clinical Research Centre

    Birmingham, B15 2SQ, United Kingdom

Conditions

Explore the condition pages connected to this study.