Heart MRI study aims to see how amyloid builds up over time

NCT ID NCT06073574

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 23 times

Summary

This study uses MRI scans to measure amyloid protein buildup in the heart of up to 150 people with a heart condition called ATTR-CM. Participants are already in a larger treatment study. The goal is to see how the amount of amyloid changes over time, not to test a new treatment. This helps researchers better understand the disease.

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Contacts and locations

Locations

  • Azienda Ospedale Università di Padova

    Padova, 35128, Italy

  • Azienda Ospedaliero - Universitaria Careggi

    Florence, 50139, Italy

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Hospital Universitario Puerta de Hierro

    Majadahonda, 28222, Spain

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Richmond Pharmacology

    London, SE1 1YR, United Kingdom

  • Royal Free London NHS Foundation Trust

    London, NW3 2QG, United Kingdom

  • Synexus - Manchester Clinical Research Centre

    Manchester, M15 6SE, United Kingdom

  • Synexus - Scotland Clinical Research Centre

    Bellshill, ML4 3NJ, United Kingdom

  • Synexus - Wales

    Cardiff, CF15 9SS, United Kingdom

  • Synexus Midlands Clinical Research Centre

    Birmingham, B15 2SQ, United Kingdom

Conditions

Explore the condition pages connected to this study.