Institute Of Liver And Biliary Sciences, India

This study aims to see if adding a drug called midodrine to the standard drug carvedilol works better than carvedilol alone at preventing early rebleeding in people with liver cirrhosis. It will enroll 210 adults with cirrhosis who have just had a serious variceal bleed. Particip…

This study is for people with sudden, severe liver failure that causes dangerous brain swelling. It will test if a more intensive version of a blood-cleansing treatment (plasma exchange) works better than the standard version. Researchers will compare how quickly brain swelling i…

This study is testing whether a daily pill called oral semaglutide can slow down or prevent worsening kidney disease in people who also have fatty liver disease (MAFLD). It will involve 90 adults with both conditions, who will be randomly assigned to receive either the pill plus …

This study is testing if adding Vitamin C to standard hospital care helps patients with severe, sudden liver failure who also have a dangerous infection and kidney injury. About 110 very sick patients will be randomly assigned to receive either standard treatment alone or standar…

This study tests if starting a blood pressure medication called midodrine early can better control dangerous fluid buildup in the abdomen (ascites) and prevent related kidney problems in people with sudden worsening of chronic liver failure. Researchers will compare midodrine plu…

This study is testing a special blood filtering treatment for people with a sudden, severe worsening of chronic liver failure. About 56 patients will be randomly assigned to receive either standard medical care alone or standard care plus the filtering treatment. The main goal is…

This study aims to understand how many adults in India with liver cirrhosis are already protected against Hepatitis A virus (HAV). For those who are not protected, researchers will test how well a single dose of the Hepatitis A vaccine works and how long the protection lasts. The…

This study aims to understand what happens to people with chronic liver disease who are urgently hospitalized with organ failure. Researchers will follow 100 patients for six months to track their health journey, looking at how their disease progresses and what factors lead to re…