Institut De Recherches Internationales Servier

This study is comparing two different drugs for adults with a type of blood and bone marrow disorder called myelodysplastic syndromes (MDS) who have a specific genetic change (IDH1 mutation) and have not yet received standard treatment. Participants will be randomly assigned to r…

This study is testing a new drug called S230815 for children aged 2-12 with a severe, hard-to-treat epilepsy caused by a change in the KCNT1 gene. The drug is injected into the spinal fluid to try to reduce seizures. The main goals are to see if the treatment is safe and how the …

This study is testing a new oral drug, S241656, alone and in combination with other cancer therapies. It aims to find a safe and effective dose for adults with advanced cancers, including lung, pancreatic, and colorectal cancers, that have specific genetic mutations like KRAS or …

This study is testing whether adding two newer drugs (ivosidenib and durvalumab) to standard chemotherapy works better for people with advanced bile duct cancer that has a specific genetic change called IDH1 mutation. The trial will first check if the combination is safe, then se…