Institut Bergonié

This phase 2 trial tests whether adding the immunotherapy drug retifanlimab to standard chemotherapy before surgery can improve outcomes for people with resectable soft-tissue sarcoma. About 66 participants will receive either chemotherapy alone or chemotherapy plus retifanlimab.…

This study planned to test a three-part treatment for advanced non-small cell lung cancer that cannot be removed by surgery. Patients would receive chemotherapy before, during, and after radiation therapy. However, the trial was withdrawn before enrolling any participants, so no …

This study was planned to test two drugs, Ezabenlimab and BI 907828, in people with advanced solid tumors like sarcoma, lung cancer, and breast cancer. The goal was to see if the combination could control the disease for at least 24 weeks. However, the study was withdrawn before …

This study looks at whether a special biopsy done with ultrasound guidance before surgery can correctly tell if a uterine tumor is cancerous or not. It involves 19 women aged 35 and older who have suspicious uterine tumors. The goal is to avoid risky surgical procedures if the tu…

This study tests a new care plan that uses technology to help doctors better manage the health of older adults (70+) who have cancer and other medical conditions. The goal is to see if this approach improves their quality of life after 6 months. About 720 people with breast, lung…

This study tests whether using a special monitor (ANI) during ovarian cancer surgery to guide pain medicine can lower the chance of chronic pain three months after the operation. About 126 women having open surgery for ovarian cancer will be randomly assigned to standard care or …

This study aimed to understand why some women develop chronic pain after breast cancer surgery. Researchers planned to track psychological and social factors in women undergoing mastectomy or lumpectomy. The goal was to help doctors better plan treatment and improve quality of li…

This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer before they start chemotherapy. Using CT scans, researchers want to see how common this condition is and if it affects treatment timing. The goal is to better understand how muscle health rela…

This study aimed to see if focused ultrasound could destroy breast tumors before mastectomy. It was planned for women with invasive breast cancer who needed a mastectomy. However, the study was withdrawn and no one took part.

This pilot study tests whether elderly cancer patients (65 and older) can use an online tool to regularly report symptoms and quality of life during treatment. Over 3 months, patients fill out weekly questionnaires on side effects and two longer surveys on well-being. The goal is…

This study was designed to measure specific proteins (chemokines) in the blood, urine, and tumors of men with prostate cancer to see how they change over time. It planned to include men starting new treatments like hormone therapy or chemotherapy. However, the study was withdrawn…

This study follows 430 people with Cowden's disease (a PTEN gene mutation) to better understand their risk of developing cancer. Researchers will track how many participants get cancer over time. The goal is to improve monitoring and care for this high-risk group.

This study brings together cancer experts to agree on standard definitions for key measurements used in cancer clinical trials, such as how long patients live without their cancer getting worse. Currently, different trials define these measurements in different ways, making it ha…

This study follows 25 people aged 70 and older who had surgery for soft tissue sarcoma in their leg. The goal is to see how the surgery changes their physical function and quality of life. Researchers use questionnaires to track recovery and identify factors that predict better o…