Heinrich-heine University, Duesseldorf

This study tests a small device placed in the heart to create a tiny passage between two upper chambers. The goal is to lower pressure inside the heart, improve its energy use, and help it pump better. The study will include 15 adults with advanced heart failure who are already o…

This study tests whether low-dose radiation to the whole brain can slow down Alzheimer's disease in people with early-onset symptoms. Fifty participants will be randomly assigned to receive either the radiation treatment or a sham procedure. Researchers will track changes in memo…

This study will follow 2,725 women aged 45-75 to see if newer forms of hormone replacement therapy (like creams, gels, and sprays) affect their risk of heart disease. The researchers want to find out if these modern treatments are safer for the heart than older methods. Participa…

This study looks at a new way to diagnose serious prostate cancer in men aged 50 to 75 with high PSA levels. Instead of always doing a biopsy, men first get an MRI. Only those with suspicious MRI results get a biopsy, and researchers compare two biopsy methods to see which finds …

This study follows 200 adults with suspected or confirmed cardiac amyloidosis, a condition where protein buildup stiffens the heart and leads to heart failure. Over two years, participants will have heart MRIs (at rest and during exercise), blood tests, and exercise breathing tes…

This study will follow 4,000 intensive care patients aged 80 and older to understand how chronic and acute heart conditions affect their long-term recovery and quality of life. Researchers will use simple tests to measure frailty and daily living skills. The goal is to better pre…