Gruppo Italiano Malattie Ematologiche Dell'adulto

This study reviews medical records of about 103 adults with Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) who received ponatinib as their first treatment in routine care. Researchers want to see how many patients achieve a deep level of cancer control (complete mol…

This study will observe 93 adults with myelofibrosis who are starting momelotinib as part of their normal care. Researchers want to see how well the drug reduces an enlarged spleen after 6 months. The goal is to understand the drug's real-world effectiveness beyond clinical trial…

This study will check if a new, highly sensitive genetic test called digital PCR can find mutations that make chronic myeloid leukemia (CML) resistant to certain treatments. Researchers will compare this test to the current standard method in 150 adults with CML whose therapy has…

This study will follow 50 adults with relapsed or refractory multiple myeloma who are receiving the drug elranatamab as part of their standard care. The main goal is to track how many infections occur during the first year of treatment and what patterns they follow. Researchers h…