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Italian study to track CAR-T success in leukemia patients

NCT ID NCT07623655

First seen Jun 04, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This observational study will follow 107 children and adults with B-cell acute lymphoblastic leukemia who are treated with approved CAR-T cell therapies in Italy. Researchers will collect data from medical records to see how many patients achieve a response. The goal is to understand how well these treatments work in everyday medical practice.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR-T cells (tisagenlecleucel, brexucabtagene autoleucel, obecabtagene autoleucel)

What this could lead to

If successful, this study could confirm how well approved CAR-T therapies work in real-world settings for B-cell acute lymphoblastic leukemia.

What could go wrong

This is an observational study, not a controlled trial, so results may be less definitive. It only looks at patients already prescribed these therapies, which may limit generalizability.

Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia Burkitt Lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.